San Francisco 49ers Schedule 2025 To 2025 Schedule. Take a look at just how juicy 2025 looks for. The san francisco 49ers’ regular season began on september 9, 2024, and will end on january 5, 2025.

And with the locking up of the cellar in the division, san francisco clinched something much more important: But which teams stand in the way on the 2024 schedule?